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Nokin M-J, Durieux F, Peixoto P, Chiavarina B, Peulen O, Blomme A, Turtoi A, Costanza B, Smargiasso N, Baiwir D, Scheijen JL, Schalkwijk CG, Leenders J, De Tullio P, Bianchi E, Thiry M, Uchida K, Spiegel DA, Cochrane JR, Hutton CA, De Pauw E, Delvenne P, Belpomme D, Castronovo V, Bellahcne A (2016) Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis

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These results, which suggest that D-Nle- Tyr-Ile-NH-(CH 2 )5-CONH 2 is likely to be relatively hydrophobic, are in agreement with the outcome of QSAR modeling estimates generated by ADMET Predictor that calculated an octano water partition coefficient of 28.18 for D-Nle-Tyr-Ile-NH-(CH 2 ) 5 -CONH 2 (Table 6)

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Toxicol Sci, 2011